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Month: February 2021

Huntingtin “coats” mitotic chromosomes when PAR break-down is inhibited

Posted on11th February 2021AuthorTamara MaiuriLeave a comment

After a long time away from the lab, it’s nice to have some new and interesting data! Details here: https://raytruantlab.ca/2021/02/11/huntingtin-coats-mitotic-chromosomes-when-par-break-down-is-inhibited/  

CategoriesHuntingtin, Huntington’s disease, Ray Truant (McMaster Univ.), Tamara Maiuri

Recent Posts

  • Huntingtin “coats” mitotic chromosomes when PAR break-down is inhibited
  • Druggability and Amino Acid Variability of the Catalytic Site of SARS-CoV-2 Nsp15 Across Coronaviruses and SARS-CoV-2 Samples – Post 26
  • Druggability and Genetic Variability at nsp9 Peptide-bound Pockets and Beta-barrel Pockets Across Coronaviruses and SARS-CoV-2 Samples – Post 25
  • Druggability and Genetic Variability of the Catalytic and Allosteric Sites of SARS-CoV-2 nsp14 Across Coronaviruses and SARS-CoV-2 Samples – Post 24
  • Project Overview: Introduction to WDR12 and WDR55 Proteins

Recent Comments

  • Setayesh Yazdani on Druggability and Amino Acid Variability of the Catalytic Site of SARS-CoV-2 Nsp15 Across Coronaviruses and SARS-CoV-2 Samples – Post 26
  • International Health on Druggability and Amino Acid Variability of the Catalytic Site of SARS-CoV-2 Nsp15 Across Coronaviruses and SARS-CoV-2 Samples – Post 26
  • International Health on 2D or not 2D: 3D is the answer
  • Setayesh Yazdani on Druggability and Genetic Variability of the ATPase Site and Central Channel of SARS-CoV-2 nsp13 Helicase Across Coronaviruses and SARS-CoV-2 Samples – Post 23
  • Charles Mowbray on Druggability and Genetic Variability of the ATPase Site and Central Channel of SARS-CoV-2 nsp13 Helicase Across Coronaviruses and SARS-CoV-2 Samples – Post 23

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      • Diamond Light Source
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      • David Dilworth
      • David Drewry
      • Edward Anderson
      • Ellie Williams
      • Evianne Rovers
      • Fang-Chi Chang
      • Hadley Sheppard
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      • Jose Brandao-Neto
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      • Katheron Intson
      • Liz Brown
      • Louisa Temme
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      • Nicola De Maio
      • Opher Gileadi
      • Peter Stogios
      • Pietro Roversi
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      • Batten disease
      • Chordoma
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      • Diffuse intrinsic pontine glioma
      • Ependymoma
      • Fibrodysplasia ossificans progressiva
      • GRIN disorder
      • Huntington’s disease
      • iPSC Disease modelling
      • Leukemia
      • Malaria
      • Parkinson’s disease and neurodevelopmental disorders
      • Primary Hyperoxaluria
      • Rare disease
    • Past
      • Dravet syndrome
  • Projects
    • Active
      • ACVR1/ALK2
      • ALS-Reproducible Antibody Platform (ALS-RAP)
      • Cell assay reports
      • Chromatin factors
      • E3 ligases
      • Epigenetic targets in Medulloblastoma
      • EZHIP
      • GTPase-GEF complex
      • HAO1
      • HDACs
      • HERO Glove
      • Huntingtin
      • Investigating Outdoor Mobility of Older Adults
      • iPSCs
      • Ligandable Genome
      • NMDA
      • NSD3
      • Open Secretion Rescue
      • PRC2
      • PRDM methyltransferases
      • PRMTs
      • Protein purification protocols
      • SARS-CoV-2 computational genomics
      • SETDB1
      • Spike
      • TBXT (brachyury) inhibitors
      • Understudied Kinases
      • USP5
      • USPs
      • WDR proteins
      • WDR41
      • XChem
    • Past
      • EGFR and GAK
      • Gene therapy for Dravet Syndrome
      • In silico PROTACs design
  • The team
  • About
  • My research in 2 minutes
    • Artem Babaian: ultra-deep search for novel coronaviruses
    • Danton Ivanochko: a chemical probe for PRDM9
    • Mandeep Mann: a chemical probe for USP5
    • Natasha Anita: depressive biomarkers in diabetes
    • Rachel Harding: 3D structure of Huntingtin
    • Setayesh Yazdani: the druggable human genome
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