Researchers from around the globe are opening up their laboratory notebooks to share their day-to-day results. Rather than wait months, even years, to share their research through journal publication as is the current practice, these scientists are posting their experimental data and protocols online and in real-time. By sharing their research in this open and timely manner, they reduce duplication of work, help foster new collaborations and cultivate a more open dialogue with others.

If you are interested in starting your own open lab notebook at openlabnotebooks.org contact matthieu.schapira@utoronto.ca. This resource is free and here to stay. To learn more:


Ten simple rules for open human health research. Bafeta A, Bobe J, Clucas J, et al., PLOS Computational Biology https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1007846


Breaking down the walls of scientific secrecy, Kelly Crowe, CBC News https://www.cbc.ca/news/health/biomedical-research-open-notebook-science-patent-drugs-pharmaceutical-academic-research-1.5176792

Open laboratory notebooks: good for science, good for society, good for scientists. Schapira et al., F1000 Researchhttps://f1000research.com/articles/8-87/v1

Open notebook science can maximize impact for rare disease projects. Harding R. PLoS Biologyhttps://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3000120


INTERVIEW: Open notebooks galore: The Structural Genomics Consortium. eLIFE.  https://elifesciences.org/interviews/89c121b4/the-structural-genomics-consortium

Open Lab Notebooks to increase impact and accelerate discovery. Schapira M. Springer Nature’s Data Dialogues

PODCAST: Structural Genomics Consortium’s Extreme Open Science Unit launch! Colper Science 2018 http://blog.colperscience.com/2018/01/18/sgcextremeopenscience/

Open science: University of Toronto researchers to publish lab notes in real time. UofT News. 19 January, 2018 https://www.utoronto.ca/news/open-science-university-toronto-researchers-publish-lab-notes-real-time

SGC researchers at University of North Carolina adopt ‘Extreme’ Open Science, share data as it happens https://pharmacy.unc.edu/news/2018/04/26/sgcunc-researchers-adopt-extreme-open-science-share-data-as-it-happens

Other open lab notebooks