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    • Setayesh Yazdani: the druggable human genome
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Setayesh Yazdani: the druggable human genome

Setayesh Yazdani at the Structural Genomics Consortium, University of Toronto, analyzes the 3D shape of human proteins to identify which can be targeted by small molecule drugs.

Learn more

  • openlabnotebooks.org/category/scientist/setayesh-yazdani
  • www.ncbi.nlm.nih.gov/pubmed/?term=Setayesh+Yazdani

Recent Posts

  • Recombinant Expression and Purification of ABHD2 from E. coli
  • Exploring the Potential of Human Helicase Ligands as Inhibitors for SARS-CoV-2 NSP13 Pt. 2
  • Exploring the Potential of Human Helicase Ligands as Inhibitors for SARS-CoV-2 NSP13
  • Multiple Sequence Alignment and Phylogenetic Tree of Human and Viral Helicases
  • Identification of N-oxide containing helicase inhibitors by large-scale virtual screening

Recent Comments

  • Erica Rebouças on Release of brachyury (TBXT) SPR Raw Data
  • Lakshi Selvaratnam on Multiple Sequence Alignment and Phylogenetic Tree of Human and Viral Helicases
  • Holli-Joi Martin on Multiple Sequence Alignment and Phylogenetic Tree of Human and Viral Helicases
  • Lakshi Selvaratnam on Multiple Sequence Alignment and Phylogenetic Tree of Human and Viral Helicases
  • Anwar Hossain on Identification of N-oxide containing helicase inhibitors by large-scale virtual screening

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  • Amy Ramsey
  • Amy Ramsey (Univ. of Toronto)
  • Amyotrophic Lateral Sclerosis (ALS)
  • Angela Kwak
  • Antoine Claessens
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  • Anwar Hossain
  • Ashley Hutchinson
  • Ben Eduful
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  • Carolyn Marks
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  • Cell assay reports
  • Cheryl Arrowsmith (Univ. of Toronto)
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  • Chromatin factors
  • Claudia Alvarez
  • COVID-19
  • Danton Ivanochko
  • David Dilworth
  • David Drewry
  • Diamond Light Source
  • Diffuse intrinsic pontine glioma
  • Dravet syndrome
  • E3 ligases
  • EGFR and GAK
  • Elizabeth Zoeller
  • Ellie Williams
  • Emory university
  • Ependymoma
  • Epigenetic targets in Medulloblastoma
  • Eve Carter
  • Evianne Rovers
  • EZHIP
  • Fang-Chi Chang
  • Fibrodysplasia ossificans progressiva
  • Gene therapy for Dravet Syndrome
  • Genna Luciani
  • Grant Mills
  • GRIN disorder
  • GTPase-GEF complex
  • Hadley Sheppard
  • HAO1
  • Haresh Ajani
  • HDACs
  • Helicases
  • Huntingtin
  • Huntington’s disease
  • In silico PROTACs design
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  • Michael Taylor (SickKids Hospital Toronto)
  • Montreal Neurological Institute
  • Nergis Imprachim
  • Nick Goldman (EBI)
  • Nicola De Maio
  • NMDA
  • Non-hormonal Contraception
  • NSD3
  • Oliver Arnolds
  • Open Secretion Rescue
  • Opher Gileadi
  • Parkinson's disease and neurodevelopmental disorders
  • Peter Brown
  • Pietro Roversi
  • Pietro Roversi (Univ. of Leicester)
  • PRC2
  • PRDM methyltransferases
  • Primary Hyperoxaluria
  • PRMTs
  • Protein purification protocols
  • Rachel Harding
  • Rare disease
  • Ray Truant (McMaster Univ.)
  • READDI-AC
  • Roslin Adamson
  • Sabrina Mackinnon
  • SARS-CoV-2 computational genomics
  • Sean O'Byrne
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  • Setayesh Yazdani
  • SETDB1
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  • Stephanie Tang
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  • Tammy Havener
  • Taraneh Hajian
  • TBXT (brachyury) inhibitors
  • Thomas M. Durcan
  • Tobias Krojer
  • TREAT-AD
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  • Home
  • Laboratories
    • Active
      • Amy Ramsey (Univ. of Toronto)
      • BCCRC, Univ. of British Columbia
      • BioZone (Univ. of Toronto)
      • Catalyst UNC Chapel Hill
      • Cheryl Arrowsmith (Univ. of Toronto)
      • CMD Oxford
      • Diamond Light Source
      • Emory university
      • Michael Taylor (SickKids Hospital Toronto)
      • Montreal Neurological Institute
      • Nick Goldman (EBI)
      • Pietro Roversi (Univ. of Leicester)
      • Qhetem, USP, Brazil
      • Ray Truant (McMaster Univ.)
      • SGC UNC Chapel Hill
      • SGC Univ. of Oxford
      • SGC Univ. of Toronto
    • Past
      • Antoine Claessens
      • SGC Karolinska
  • People
    • Active
      • Alfredo Picado
      • Alma Seitova
      • Amy Ramsey
      • Angela Kwak
      • Anwar Hossain
      • Arunima
      • Ashley Hutchinson
      • Ben Eduful
      • Benjamin Dai
      • Claudia Alvarez
      • Danton Ivanochko
      • David Dilworth
      • David Drewry
      • Edward Anderson
      • Elizabeth Zoeller
      • Ellie Williams
      • Eve Carter
      • Evianne Rovers
      • Fang-Chi Chang
      • Grant Mills
      • Hadley Sheppard
      • Jong Fu Wong
      • Jose Brandao-Neto
      • Joseph Newman
      • Katheron Intson
      • Lakshi Selvaratnam
      • Liz Brown
      • Louisa Temme
      • Madison Edwards
      • Magdalena Szewczyk
      • Mandeep Mann
      • Nergis Imprachim
      • Nicola De Maio
      • Oliver Arnolds
      • Opher Gileadi
      • Peter Brown
      • Peter Stogios
      • Pietro Roversi
      • Rachel Harding
      • Sabrina Mackinnon
      • Serap Beldar
      • Setayesh Yazdani
      • Stephen R. Armstrong
      • Suzanne Ackloo
      • Tamara Maiuri
      • Tammy Havener
      • Taraneh Hajian
      • Thiago dos Santos
      • Thomas M. Durcan
      • Tobias Krojer
      • Victoria Vu
      • Yuanye Yan
    • Past
      • Antoine Claessens
      • Carla Alamillo
      • Carmen Jimenez Antunez
      • Carolyn Marks
      • Genna Luciani
      • Haresh Ajani
      • Jacob McAuley
      • Jolene Ho
      • Kaleb Naegeli
      • Megha Abbey
      • Nirav Kapadia
      • Roslin Adamson
      • Sean O’Byrne
      • Wen Yih Aw
  • Diseases
    • Active
      • Alzheimer’s disease
      • Amyotrophic Lateral Sclerosis (ALS)
      • Batten disease
      • Chordoma
      • COVID-19
      • Diffuse intrinsic pontine glioma
      • Ependymoma
      • Fibrodysplasia ossificans progressiva
      • GRIN disorder
      • Huntington’s disease
      • Influenza
      • iPSC Disease modelling
      • Leukemia
      • Malaria
      • Parkinson’s disease and neurodevelopmental disorders
      • Primary Hyperoxaluria
      • Rare disease
    • Past
      • Dravet syndrome
  • Projects
    • Active
      • ACVR1/ALK2
      • ALS-Reproducible Antibody Platform (ALS-RAP)
      • Cell assay reports
      • Chromatin factors
      • E3 ligases
      • Epigenetic targets in Medulloblastoma
      • EZHIP
      • GTPase-GEF complex
      • HAO1
      • HDACs
      • Helicases
      • HERO Glove
      • Huntingtin
      • Influenza computational genomics
      • Investigating Outdoor Mobility of Older Adults
      • iPSCs
      • Ligandable Genome
      • NMDA
      • Non-hormonal Contraception
      • NSD3
      • Open Secretion Rescue
      • PRC2
      • PRDM methyltransferases
      • PRMTs
      • Protein purification protocols
      • READDI-AC
      • SARS-CoV-2 computational genomics
      • SARS-CoV-2 NSP14
      • SETDB1
      • Spike
      • TBXT (brachyury) inhibitors
      • Toronto Open Access SARS-CoV-2 Protein Manufacturing Center
      • TREAT-AD
      • Understudied Kinases
      • USP5
      • USPs
      • WDR proteins
      • WDR41
      • XChem
    • Past
      • EGFR and GAK
      • Gene therapy for Dravet Syndrome
      • In silico PROTACs design
  • The team
  • About
  • My research in 2 minutes
    • Artem Babaian: ultra-deep search for novel coronaviruses
    • Danton Ivanochko: a chemical probe for PRDM9
    • Mandeep Mann: a chemical probe for USP5
    • Natasha Anita: depressive biomarkers in diabetes
    • Rachel Harding: 3D structure of Huntingtin
    • Setayesh Yazdani: the druggable human genome
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