A growing team of groundbreaking scientists around the world are now sharing their lab notebooks online
Background The Structural Genomics Consortium (SGC) has been funded by the Bill & Melinda Gates Foundation to research Women’s and Children’s Health, focusing on the advancement of drug discovery in reproductive biology and disease, child development, and childhood diseases. The SGC plans to generate protein reagents and chemical probes for several potential drug targets for Read More …
Characterization and Assessment of KCNU1/SLO3 as a Potential Non-hormonal Contraceptive Target Introduction Project Proposal The Structural Genomics Consortium (SGC) has recently embarked on its first research project in reproductive biology as a part of the SGC’s new open science Women’s and Children’s Health Program (WCHP). This program, which was generously funded by the Bill & Read More …
Background: Ovastacin is an oocyte-specific protease involved in sperm adhesion and fertilization. Research into the ovastacin’s protease function suggest it acts on the post-fertilization cleavage of ZP2 via cortical granule exocytosis1. Cleaved ZP2 then causes hardening of the zona pellucida and is then unable to support further sperm binding2. Zona pellucida regulation is critical for Read More …
