Gone bionic
Dear readers, I had unfortunately torn my ACL for the silliest of reasons and have decided to use up my annual leaves for more time off. I will therefore be on hiatus till October. Adios! Jong Fu
Month: September 2018
Is huntingtin a PAR-binding protein?
Is huntingtin a PAR-binding protein?
Searching far and wide for proteins that bind huntingtin
Searching far and wide for proteins that bind huntingtin
Speaking at the annual conference of the Society for the Study of Inborn Errors of Metabolism (SSIEM)
Hello again! This week I am in sunny, sunny Athens attending the SSIEM annual conference that brings together renowned experts in inborn errors of metabolism from around the world to present their latest pre-clinical and clinical research. I was fortunate enough to receive a generous travel grant from the SSIEM to give a talk this Read More …
Identifying fragments that bind to HAO1 by x-ray crystallography
In this post, I would like to share my recent work on HAO1 fragment screening by crystallography, as a means to identify inhibitor starting points. So why fragment screening by x-ray crystallography? Well there are two components to my method of choice: Fragments instead of complex compounds provide good starting chemistry Fragments are less than Read More …