CaMKK2 Inhibitor Series
The line up of inhibitor series (hinge binders) for CaMKK2 currently being pursued include: furopyridine, azaindole (pyrrolopyridine), quinoline, triazolopyridazine, imidazopyrazine, pyrazolopyrimidine. Figure 1. Figure 1: CaMKK2 hinge binders As part of our structure and activity relationships (SAR), we continue to build diversity on the pyridine ring for the furopyridine series, and new compounds added to Read More …