ROS-dependent huntingtin interactions in mouse striatal cells
ROS-dependent huntingtin interactions in mouse striatal cells
Huntington’s disease
Background on HTT and HD
Before I get into the details of my project and share my results, I would first like to give a brief background on HTT. What is HTT? HTT is a protein that is encoded by HTT, the gene, and it stands for huntingtin. This protein is heavily implicated in Huntington’s disease (HD), a disease Read More …
Project Overview: Role of HTT in neurological disorders
Hi everyone! As part of SGC’s Extreme Open Science program, I’m going to be giving live updates on my project on the role of HTT in neurological disorders. As this is my first blogpost, I’ll start by giving an overview of my project. The focus of my project is HTT and its role in neurological Read More …
Update: Measuring DNA repair capacity and visualizing huntingtin in HD patient cells
Update: Measuring DNA repair capacity and visualizing huntingtin in HD patient cells
Visualizing real huntingtin protein in cells from an HD patient
Visualizing real huntingtin protein in cells from an HD patient
Measuring the rate of DNA repair in HD cells
Measuring the rate of DNA repair in HD cells
Pulling huntingtin-associated DNA repair proteins out of HD patient cells
Pulling huntingtin-associated DNA repair proteins out of HD patient cells
Testing oxidative stress conditions for huntingtin-DNA repair protein interactions
Testing oxidative stress conditions for huntingtin-DNA repair protein interactions
Real Time Report: The Oxidative Stress Interactome Project
Real Time Report: The Oxidative Stress Interactome Project